Citrus changshan huyou extract

1 paper5 findings

A mouse study reports that Citrus changshan huyou extract reduces aortic plaques, aortic inflammation and senescence, and weight gain in high-fat diet-induced ApoE−/− mice, while activating intestinal GLP-1 and incretin signalling. Five findings come from one lab, with no opposing finding or human results.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Animals1

Outcomes

5

GLP-1 and incretin signalling

upin mice1

1 study

Citrus changshan huyou extract activates GLP-1 and incretin signalling in mice.
Animalsintestine
Citrus Changshan Huyou extracts as natural GLP-1R agonists attenuate atherosclerosis via the GLP-1R/PKA/CREB pathway: a functional food perspective
Frontiers in nutrition5 Aug 2026

More on GLP-1 and incretin signalling

Inflammation

downin mice1

1 study

Citrus changshan huyou extract inhibits inflammation in mice.
Animalsin high-fat diet-induced ApoE−/− miceaortic tissues
Citrus Changshan Huyou extracts as natural GLP-1R agonists attenuate atherosclerosis via the GLP-1R/PKA/CREB pathway: a functional food perspective
Frontiers in nutrition5 Aug 2026

More on Inflammation

Cellular senescence

downin mice1

1 study

Citrus changshan huyou extract inhibits cellular senescence in mice.
Animalsin high-fat diet-induced ApoE−/− miceaortic tissues
Citrus Changshan Huyou extracts as natural GLP-1R agonists attenuate atherosclerosis via the GLP-1R/PKA/CREB pathway: a functional food perspective
Frontiers in nutrition5 Aug 2026

More on Cellular senescence

Weight gain

downin mice1

1 study

Citrus changshan huyou extract decreases weight gain in mice.
Animalsin high-fat diet-induced ApoE−/− mice
Citrus Changshan Huyou extracts as natural GLP-1R agonists attenuate atherosclerosis via the GLP-1R/PKA/CREB pathway: a functional food perspective
Frontiers in nutrition5 Aug 2026

Atherosclerotic plaque lesions

downin mice1

1 study

Citrus changshan huyou extract decreases atherosclerotic plaque lesions in mice.
Animalsin high-fat diet-induced ApoE−/− miceaorta
Citrus Changshan Huyou extracts as natural GLP-1R agonists attenuate atherosclerosis via the GLP-1R/PKA/CREB pathway: a functional food perspective
Frontiers in nutrition5 Aug 2026

Latest

1 in 12 months

Frontiers in Nutrition20 Aug

Citrus Changshan Huyou extracts as natural GLP-1R agonists attenuate atherosclerosis via the GLP-1R/PKA/CREB pathway: a functional food perspective

Experiments in miceAtherosclerosis