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Chrysophanol

Intervention

1 paper3 findings

PubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

Outcomes

2

Lifespan

upin mice1upin worms1

1 study

  1. Chrysophanol extends lifespan in mice.

    “Chr promoted longevity in natural aging mice, doxorubicin-induced aging mice, and transgenic mice”

    Animals

    Chrysophanol delays aging via insulin/IGF-1 signaling pathway

    Free radical biology & medicine12 Mar 2025

  2. Chrysophanol extends lifespan in worms.

    “we discovered that Chr extends both lifespan and healthspan in Caenorhabditis elegans by activating the DAF-2/DAF-16 insulin signaling pathway.”

    Model organisms

    Chrysophanol delays aging via insulin/IGF-1 signaling pathway

    Free radical biology & medicine12 Mar 2025

Healthspan

upin worms1

1 study

  1. Chrysophanol improves healthspan in worms.

    “we discovered that Chr extends both lifespan and healthspan in Caenorhabditis elegans”

    Model organisms

    Chrysophanol delays aging via insulin/IGF-1 signaling pathway

    Free radical biology & medicine12 Mar 2025

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