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Chronic disease self-management programs

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country

Outcomes

3

Diastolic blood pressure

downin humans1

1 study

  1. Chronic disease self-management programs decrease diastolic blood pressure in humans (−4.3 mm Hg; effect size −0.51 (95% CI −0.73 to −0.30)).

    “decreased diastolic blood pressure by 4.3 mm Hg (effect size, -0.51 [CI, -0.73 to -0.30]).”

    Reviewhypertension

    Meta-analysis: chronic disease self-management programs for older adults

    Annals of internal medicine20 Sep 2005

More on Diastolic blood pressure

Systolic blood pressure

downin humans1

1 study

  1. Chronic disease self-management programs decrease systolic blood pressure in humans (−5 mm Hg; effect size −0.39 (95% CI −0.51 to −0.28)).

    “Self-management interventions decreased systolic blood pressure by 5 mm Hg (effect size, -0.39 [CI, -0.51 to -0.28])”

    Reviewhypertension

    Meta-analysis: chronic disease self-management programs for older adults

    Annals of internal medicine20 Sep 2005

More on Systolic blood pressure

Hemoglobin A1c

downin humans1

1 study

  1. Chronic disease self-management programs decrease hemoglobin A1c in humans (Effect size −0.36 (95% CI −0.52 to −0.21); hemoglobin A1c reduction about 0.81%).

    “Self-management interventions led to a statistically and clinically significant pooled effect size of -0.36 (95% CI, -0.52 to -0.21) for hemoglobin A1c”

    Reviewdiabetes mellitus

    Meta-analysis: chronic disease self-management programs for older adults

    Annals of internal medicine20 Sep 2005

More on Hemoglobin A1c

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