Chlorpyrifos

  • 2 independent labs in 2 countries
  • Funders: National Natural Science Foundation of China and 4 more
  • Animals1
  • Model organisms1

Outcomes

4

Lifespan

downin B. calyciflorus1downin C. dabryi1downin fish1

3 studies
  1. Chlorpyrifos shortens lifespan in C. dabryi.

    “chronic low-dose chlorpyrifos exposure induced telomere degradation and reduced survival in a dose- and physiological age-dependent manner”

    Animalschronic low-dose exposure

    Chronic low-dose exposure to chlorpyrifos reduces life span in a wild fish by accelerating aging

    Science (New York, N.Y.)15 Jan 2026

  2. Chlorpyrifos shortens lifespan in fish.

    “Low doses of insecticide speed fish aging and death”

    Reviewlow doses

    Low doses of insecticide speed fish aging and death

    Science (New York, N.Y.)15 Jan 2026

  3. Chlorpyrifos protects against lifespan in B. calyciflorus.

    “the heat spike-induced reductions in survival, fecundity, lifespan, the proportion of rotifers producing offspring, and the intrinsic population growth rate were no longer significant when combined with subsequent chlorpyrifos exposure.”

    Model organismsfollowing a 12 h heat spike (32 °C) in parental generation50 μg/L36 h

    Hormetic Effects of the Pesticide Chlorpyrifos Counteract the Adverse Effects of a Heat Spike Both within and across Generations in a Freshwater Rotifer

    Environmental science & technology12 Aug 2025

Telomere length

downin C. dabryi1

1 study
  1. Chlorpyrifos decreases telomere length in C. dabryi.

    “Field investigations showed that fish populations of lake skygazer (Culter dabryi) with chronic low-dose chlorpyrifos loads had shortened telomeres”

    Animalschronic low-dose exposure

    Chronic low-dose exposure to chlorpyrifos reduces life span in a wild fish by accelerating aging

    Science (New York, N.Y.)15 Jan 2026

More on Telomere length

Intrinsic population growth rate

upin B. calyciflorus1

1 study
  1. Chlorpyrifos increases intrinsic population growth rate in B. calyciflorus.

    “In contrast, chlorpyrifos exposure elicited hormetic responses, shortening the time to the first brood and increasing the intrinsic population growth rate.”

    Model organisms50 μg/L36 h

    Hormetic Effects of the Pesticide Chlorpyrifos Counteract the Adverse Effects of a Heat Spike Both within and across Generations in a Freshwater Rotifer

    Environmental science & technology12 Aug 2025

Survival

downin B. calyciflorus1

1 study
  1. Chlorpyrifos protects against survival in B. calyciflorus.

    “the heat spike-induced reductions in survival, fecundity, lifespan, the proportion of rotifers producing offspring, and the intrinsic population growth rate were no longer significant when combined with subsequent chlorpyrifos exposure.”

    Model organismsfollowing a 12 h heat spike (32 °C) in parental generation50 μg/L36 h

    Hormetic Effects of the Pesticide Chlorpyrifos Counteract the Adverse Effects of a Heat Spike Both within and across Generations in a Freshwater Rotifer

    Environmental science & technology12 Aug 2025

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