Chemogenetic modulation of dorsal raphe serotonin neurons

Exposure

1 paper1 finding

  • 1 lab in 1 country
  • Funders: Alberta Children's Hospital Research Institute and others
  • Animals1

Outcomes

1

Physical activity

downin mice1

1 study
  1. Chemogenetic modulation of dorsal raphe serotonin neurons decrease physical activity in mice.

    “Chemogenetically mimicking this 5-HT DR tone in young adult mice produced an older adult PA profile.”

    Animalsmimicking older-mouse serotonin neuronal tonedorsal raphe serotonin neurons

    Brain serotonin circuit reverses decline in physical activity with age

    bioRxiv (Cold Spring Harbor Laboratory)27 Dec 2025Preprint

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