Cardiosphere-derived cell-derived extracellular vesicles
1 paper3 findings
- 1 lab in 1 country
- Funders: Cedars-Sinai Medical Center and 3 more
- Animals1
Outcomes
3Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Cardiosphere-derived cell-derived extracellular vesicles decrease cellular senescence in human cells.
“EVs secreted by young CDCs exert broad-ranging anti-aging effects in aged rodents and in cellular models of human senescence.”
Cellsin aged human CSPCs and progeric fibroblasts
Scientific reports28 Jul 2023
Heart function
upin rats1
1 study
Heart function
upin rats1
Cardiosphere-derived cell-derived extracellular vesicles improve heart function in rats.
“Treatment with young CDC-EVs induce structural and functional improvements in the heart, lungs, skeletal muscle, and kidneys of old rats”
Animals4-months
Scientific reports28 Jul 2023
Lifespan
upin rats1
1 study
Lifespan
upin rats1
Cardiosphere-derived cell-derived extracellular vesicles extend lifespan in rats.
“Lifespan was prolonged.”
Animals4-months
Scientific reports28 Jul 2023
Latest
Scientific Reports
Rejuvenating effects of young extracellular vesicles in aged rats and in cellular models of human senescence
Experiments in ratsExtracellular vesicles