Luseogliflozin + caloric restriction
1 paper3 findings
- 1 lab in 1 country
- Funders: Japan Society for the Promotion of Science and 2 more
- Animals1
Outcomes
3Creatinine clearance
upin rats1
1 study
Creatinine clearance
upin rats1
Luseogliflozin + caloric restriction increases creatinine clearance in rats.
“increased creatinine clearance vs OLETF ad lib”
Animalsvs OLETF ad libluseogliflozin + 30% CRmales
Molecular and cellular endocrinologyOct 29, 2022
Insulin resistance
downin rats1
1 study
Insulin resistance
downin rats1
Luseogliflozin + caloric restriction decreases insulin resistance in rats.
“decreased insulin resistance index (IRI)”
Animalsvs OLETF ad libluseogliflozin + 30% CRmales
Molecular and cellular endocrinologyOct 29, 2022
Systolic blood pressure
downin rats1
1 study
Systolic blood pressure
downin rats1
Luseogliflozin + caloric restriction decreases systolic blood pressure in rats.
“Simultaneous treatments decreased SBP in OLETF vs SGLT2i alone”
Animalsvs SGLT2i aloneluseogliflozin + 30% CRmales
Molecular and cellular endocrinologyOct 29, 2022
Latest
Molecular and Cellular Endocrinology
Simultaneous SGLT2 inhibition and caloric restriction improves insulin resistance and kidney function in OLETF rats
Experiments in ratsDietary restriction