AgingResearch.NewsJoin free

Blockade of ca2+ channels

Intervention

1 paper studies it1 finding

Across all fields, 1 paper: none in people yet, 1 in animals

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Animals1

Outcomes

1

Mitochondrial function

upin C. porcellus cells1

1 study

  1. Blockade of ca2+ channels improve mitochondrial function in C. porcellus cells.

    “However, subsequent blockade of Ca2+ channels in cells resulted in downregulation of HIF-1α, ATP2A2, P53, α-SMA, Caspase-3, and BAX expression, alongside ameliorated mitochondrial function and morphology.”

    Cellsin pilocarpine-treated cellsciliary muscle

    Pilocarpine mediated excessive calcium accumulation leads to ciliary muscle cell senescence and apoptosis

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Latest

Related