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Bisindolylmaleimide x

Intervention

1 paper studies it1 finding

Across all fields, 1 paper: none in people yet, 1 in animals

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Anhui Medical University and 2 more
  • Animals1

Outcomes

1

Cognitive impairment

downin mice1

1 study

  1. Bisindolylmaleimide x decreases cognitive impairment in mice.

    “Deficits in postoperative cognition, hippocampal mitochondria, autophagy, and synapse were significantly attenuated after pharmacological inhibition of PKC or genetic deletion of PKR.”

    Animalspostoperative cognitive deficits

    The role of PKC/PKR in aging, Alzheimer's disease, and perioperative neurocognitive disorders

    Frontiers in aging neuroscience

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