Betel quid

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Humans1

Outcomes

Lifespan

downin humans1

1 study

Betel quid shortens lifespan in humans (-5.93 years).
“Life expectancy of chewers was shorter than non-chewers by 5.93 years at age 20 and 5.55 years at age 40.”
Humansmales
Cancer risks from betel quid chewing beyond oral cancer: a multiple-site carcinogen when acting with smoking
Cancer causes & control : CCC11 May 2010

Associations

Oral cancer

upin humans1HR 12.52

1 study

Betel quid raises the risk of oral cancer in humans (HR = 12.52).
“Risks of at least six cancer sites were increased among chewers: oral cavity (HR = 12.52), esophagus (HR = 5.64), liver (HR = 2.27), pancreas (HR = 2.67), larynx (HR = 6.24), and lung (HR = 2.43)”
Humansmales
Cancer risks from betel quid chewing beyond oral cancer: a multiple-site carcinogen when acting with smoking
Cancer causes & control : CCC11 May 2010

Latest

Cancer Causes & Control11 May

Cancer risks from betel quid chewing beyond oral cancer: a multiple-site carcinogen when acting with smoking

Cohort study of 177,271 peopleOral cancer

Paper

Betel quid

Outcomes

Associations

Latest

Cancer risks from betel quid chewing beyond oral cancer: a multiple-site carcinogen when acting with smoking

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