Navitoclax + BAM15
- 1 lab in 1 country
- Funders: Medical Research Council and 1 more
- Animals1
Outcomes
2Cognitive function
upin mice1
1 study
Cognitive function
upin mice1
Navitoclax + BAM15 improves cognitive function in mice.
“Cognitive performance was preserved in nutraceutical-treated mice and improved shortly after senolytic treatment.”
Animalsoverweight, naturally aged C57Bl/6J miceshortly after treatmentmales
Preprints.org31 Dec 2025Preprint
Lifespan
upin mice1
1 study
Lifespan
upin mice1
Navitoclax + BAM15 extends lifespan in mice (+18–21% median lifespan across the two interventions versus controls).
“Both interventions improved survival compared to controls (median lifespan +18–21%)”
Animalsoverweight, naturally aged C57Bl/6J mice following a switch to soaked foodtwo short coursesmales
Preprints.org31 Dec 2025Preprint
Latest
1 in 12 monthsPreprints.org
Rescuing Healthspan in Obese, Aged Mice: A Comparison between Multi-Ingredient Nutraceuticals and Senolytic Interventions
Preprint: experiments in miceInterventions