Navitoclax + BAM15

  • 1 lab in 1 country
  • Funders: Medical Research Council and 1 more
  • Animals1

Outcomes

2

Cognitive function

upin mice1

1 study
  1. Navitoclax + BAM15 improves cognitive function in mice.

    “Cognitive performance was preserved in nutraceutical-treated mice and improved shortly after senolytic treatment.”

    Animalsoverweight, naturally aged C57Bl/6J miceshortly after treatmentmales

    Rescuing Healthspan in Obese, Aged Mice: A Comparison between Multi-Ingredient Nutraceuticals and Senolytic Interventions

    Preprints.org31 Dec 2025Preprint

Lifespan

upin mice1

1 study
  1. Navitoclax + BAM15 extends lifespan in mice (+18–21% median lifespan across the two interventions versus controls).

    “Both interventions improved survival compared to controls (median lifespan +18–21%)”

    Animalsoverweight, naturally aged C57Bl/6J mice following a switch to soaked foodtwo short coursesmales

    Rescuing Healthspan in Obese, Aged Mice: A Comparison between Multi-Ingredient Nutraceuticals and Senolytic Interventions

    Preprints.org31 Dec 2025Preprint

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