Auxin-based gene expression system

Auxin-based gene expression system shortens lifespan in flies.

“We also observe phenotypes from activating the AGES machinery, including shortened lifespan”

Model organismsActivation of AGES machinery

AGES for Ageing: Evaluating the auxin-inducible gene expression system for use in Drosophila ageing studies

bioRxiv (Cold Spring Harbor Laboratory)·29 May 2026Preprint

Auxin-based gene expression system induces transgene expression in flies.

“AGES can effectively induce transgene expression across a range of ages, albeit with tissue-specific efficiency.”

Model organismsTissue-specific efficiency

AGES for Ageing: Evaluating the auxin-inducible gene expression system for use in Drosophila ageing studies

bioRxiv (Cold Spring Harbor Laboratory)·29 May 2026Preprint