ATase1/ATase2 inhibition
1 paper1 finding
- 1 lab in 1 country
- Funders: American Diabetes Association and others
- Animals1
Outcomes
1Autophagy
upin mice1
1 study
Autophagy
upin mice1
ATase1/ATase2 inhibition improves autophagy in mice.
“Inhibition of ATase1/ATase2 acetyltransferase enzymes downstream of AT-1 restores reticulophagy and rescues the phenotype of the animals.”
Animalsin AT-1 overexpressing mice
Increased transport of acetyl-CoA into the endoplasmic reticulum causes a progeria-like phenotype
Aging cellJul 27, 2018