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Asparagus officinalis

Asparagus officinalis has been studied in 2 papers since 2021: 1 trial in people, 1 in animals; 1 in the past year. The newest story, Nov 1, 2026: “Asparagus stem extract may improve memory in healthy adults”.

Intervention

2 papers study it5 findingsUpdated

1 new paper in 30 daysSee all 2

“the ETAS group showed significantly greater improvements in composite memory score at 6 wk (difference: 12.8 points, p=0.006) and 12 wk (difference: 9.0 points, p=0.048).”
Intake of ETAS® Improves Cognitive Function in Healthy Middle-Aged and Older Adults: A Randomized, Double-Blind, Placebo-Controlled TrialJournal of Nutritional Science and Vitaminology2026doi:10.3177/jnsv.72.415

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 2 independent labs in 2 countries
  • 2 of 5 findings with company ties
  • Human trial1
  • Animals1

Studies in people

1 study gave asparagus officinalis to people and measured what changed.

  • up: Improves composite memory scoreBetween-group difference: 12.8 points at 6 weeks; 9.0 points at 12 weeks

    no change: Has no effect on treatment-related adverse eventsNo ETAS-related adverse events reported

    Randomized trial60 people≥40 years12 weeks

    Midlife adults; Older adults; Healthy adults with normal cognitive function

    Journal of Nutritional Science and Vitaminology, Oct 31, 2026

What did studies of Asparagus officinalis find?

5

Studies of Asparagus officinalis measured 5 outcomes; the most studied are treatment-related adverse events (1 study), composite memory score (1) and inflammation (1).

Treatment-related adverse events

no changein humans1

1 study

  1. Asparagus officinalis showed no clear effect on treatment-related adverse events in humans (Healthy adults with normal cognitive function) (No ETAS-related adverse events reported).

    “No adverse events related to ETAS were reported.”

    Human trialHealthy adults with normal cognitive functionstandardized stem extract300 mg/day12 weeks

    Asparagus stem extract may improve memory in healthy adults

    Journal of Nutritional Science and Vitaminology

Composite memory score

upin humans1

1 study

  1. Asparagus officinalis improves composite memory score in humans (Healthy adults with normal cognitive function; compared with placebo) (Between-group difference: 12.8 points at 6 weeks; 9.0 points at 12 weeks).

    “the ETAS group showed significantly greater improvements in composite memory score at 6 wk (difference: 12.8 points, p=0.006) and 12 wk (difference: 9.0 points, p=0.048).”

    Human trialHealthy adults with normal cognitive function; compared with placebostandardized stem extract300 mg/day12 weeksn = 60

    Asparagus stem extract may improve memory in healthy adults

    Journal of Nutritional Science and Vitaminology

Inflammation

no changein mice1

1 study

  1. Asparagus officinalis showed no clear effect on inflammation in mice.

    “Overall, no significant differences in general health or clinical signs of inflammation between the two groups were observed.”

    Animalsfreshly squeezed domestic white asparagus juice, 5% (v/v)5% (v/v)60 daysn = 32

    Effects of ad libitum Free-Choice Access to Freshly Squeezed Domestic White Asparagus Juice on Intestinal Microbiota Composition and Universal Bio-Markers of Immuno-Metabolic Homeostasis and General Health in Middle-Aged Female and Male C57BL/6 Mice

    Endocrine, metabolic & immune disorders drug targets

More on Inflammation

Short-chain fatty acids

upin mice1

1 study

  1. Asparagus officinalis increases short-chain fatty acids in mice.

    “Asparagus juice significantly elevated the caecal contents of SCFAs.”

    Animalsfreshly squeezed domestic white asparagus juice, 5% (v/v)cecum5% (v/v)60 daysn = 32

    Effects of ad libitum Free-Choice Access to Freshly Squeezed Domestic White Asparagus Juice on Intestinal Microbiota Composition and Universal Bio-Markers of Immuno-Metabolic Homeostasis and General Health in Middle-Aged Female and Male C57BL/6 Mice

    Endocrine, metabolic & immune disorders drug targets

More on Short-chain fatty acids

Liver-to-body weight ratio

downin mice1

1 study

  1. Asparagus officinalis decreases liver-to-body weight ratio in mice.

    “The liver to body weight ratio in asparagus juice-drank mice was lowered.”

    Animalsfreshly squeezed domestic white asparagus juice, 5% (v/v)liver5% (v/v)60 daysn = 32

    Effects of ad libitum Free-Choice Access to Freshly Squeezed Domestic White Asparagus Juice on Intestinal Microbiota Composition and Universal Bio-Markers of Immuno-Metabolic Homeostasis and General Health in Middle-Aged Female and Male C57BL/6 Mice

    Endocrine, metabolic & immune disorders drug targets

More on Liver-to-body weight ratio

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 1Nov 2026: 01 paper in 12 months
Journal of Nutritional Science and Vitaminology

Asparagus stem extract may improve memory in healthy adults

Memory scores improved 9.0 points more with the extract than with placebo after 12 weeks in a randomized trial.Memory scores improved 9.0 points more with the extract than with placebo after 12 weeks in a randomized trial.

Randomized trial · 60 peopleInterventions
Paper

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