Arundic acid

1. Arundic acid prevents stroke in rats.

   “These data indicate that arundic acid can prevent hypertension-induced stroke”

   Animalsin stroke-prone spontaneously hypertensive rats

   Immunohistochemical analysis of brain lesions using S100B and glial fibrillary acidic protein antibodies in arundic acid- (ONO-2506) treated stroke-prone spontaneously hypertensive rats

   Journal of neural transmission (Vienna, Austria : 1996)·6 Aug 2009

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1. Arundic acid decreases blood pressure in rats.

   “Blood pressure decreased after administration of arundic acid in the high-dose group (100 mg/kg/day arundic acid), but not in the low-dose group (30 mg/kg/day).”

   Animalsin stroke-prone spontaneously hypertensive rats100 mg/kg/day

   Immunohistochemical analysis of brain lesions using S100B and glial fibrillary acidic protein antibodies in arundic acid- (ONO-2506) treated stroke-prone spontaneously hypertensive rats

   Journal of neural transmission (Vienna, Austria : 1996)·6 Aug 2009

More on Blood pressure

1. Arundic acid decreases gliosis in rats.

   “An increase in brain tissue weight was inhibited concomitant with a lower rate of gliosis/hemosiderin deposit/scarring in brain lesions.”

   Animalsin stroke-prone spontaneously hypertensive ratsbrain

   Immunohistochemical analysis of brain lesions using S100B and glial fibrillary acidic protein antibodies in arundic acid- (ONO-2506) treated stroke-prone spontaneously hypertensive rats

   Journal of neural transmission (Vienna, Austria : 1996)·6 Aug 2009

1. Arundic acid extends lifespan in rats.

   “Arundic acid extended the average life span of SHRSP.”

   Animalsin stroke-prone spontaneously hypertensive rats

   Immunohistochemical analysis of brain lesions using S100B and glial fibrillary acidic protein antibodies in arundic acid- (ONO-2506) treated stroke-prone spontaneously hypertensive rats

   Journal of neural transmission (Vienna, Austria : 1996)·6 Aug 2009