Apolipoprotein d
Intervention1 paper1 finding
- Cells1
Outcomes
1Age-related pathology
upin mice1
1 study
Age-related pathology
upin mice1
Apolipoprotein d induces age-related pathology in mice.
Animalsskeletal muscle
ApoD drives cellular aging phenotypes through a nuclear mechanotransduction feedback loop · bioRxiv : the preprint server for biology · 10 Sep 2026 · Preprint
Latest
1ApoD drives cellular aging phenotypes through a nuclear mechanotransduction feedback loop
In cultured fibroblasts and mice, apolipoprotein D triggers SUN1 accumulation, reinforcing a signaling cycle that alters gene expression and cellular polarity.