Antisense oligonucleotide targeting C2ORF74

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

1

Obesity

downin mice1

1 study
  1. Antisense oligonucleotide targeting C2ORF74 protects against obesity in mice.

    “antisense oligonucleotide (ASO) targeting C2orf74 protects male mice from HFD-induced obesity.”

    Animalshigh-fat dietmales

    C2orf74 orchestrates germ-Leydig crosstalk to inhibit white adipose tissue browning in male mice

    Nature communications21 May 2026

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