ANTI-CD47 antibody
2 papers4 findings
- 1 lab in 1 country
- Funders: National Institute of Neurological Disorders and Stroke and 1 more
- Humans1
- Animals1
Outcomes
4Neuronal loss
downin rats1
1 study
Neuronal loss
downin rats1
ANTI-CD47 antibody decreases neuronal loss in rats.
“reduced neuronal loss in the hippocampal CA1 region.”
Animalsintraventricular hemorrhagehippocampusday 3males
CD47 inhibiting antibody alleviates brain injury after intraventricular hemorrhage in aged rats
Experimental neurology25 Apr 2026
Ventricular wall damage
downin rats1
1 study
Ventricular wall damage
downin rats1
ANTI-CD47 antibody decreases ventricular wall damage in rats.
“CD47 inhibition further attenuated ventricular wall damage on day 3”
Animalsintraventricular hemorrhageventricular wallday 3males
CD47 inhibiting antibody alleviates brain injury after intraventricular hemorrhage in aged rats
Experimental neurology25 Apr 2026
Intraventricular hematoma volume
downin rats1
1 study
Intraventricular hematoma volume
downin rats1
ANTI-CD47 antibody decreases intraventricular hematoma volume in rats.
“Treatment with CD47 inhibition significantly reduced intraventricular T2* hematoma volume on both days 1 and 3”
Animalsintraventricular hemorrhagebraindays 1 and 3males
CD47 inhibiting antibody alleviates brain injury after intraventricular hemorrhage in aged rats
Experimental neurology25 Apr 2026
Hydrocephalus
downin rats1
1 study
Hydrocephalus
downin rats1
ANTI-CD47 antibody decreases hydrocephalus in rats.
“CD47-blocking antibody markedly alleviated hemorrhage-induced hydrocephalus in aged rats by day 3 after IVH.”
Animalsintraventricular hemorrhagebrain3 daysmales
CD47 inhibiting antibody alleviates brain injury after intraventricular hemorrhage in aged rats
Experimental neurology25 Apr 2026