ANTAGOMIR-122-5P

Intervention1 paper2 findings

Animals1

Outcomes

2

Cellular senescence

downin mice1Very low certainty

1 study

ANTAGOMIR-122-5P decreases cellular senescence in mice.
Animalsin pregnant mice with AT1-AA-induced preeclampsia
MicroRNA-122-5p Targets FOXO3 to Mediate Podocyte Senescence and Proteinuria Induced by Angiotensin II Type 1 Receptor Autoantibodies in Preeclampsia · Reproductive sciences (Thousand Oaks, Calif.) · 22 Sep 2026

Cellular senescence →

Systolic blood pressure

downin mice1Very low certainty

1 study

ANTAGOMIR-122-5P decreases systolic blood pressure in mice.
Animalsin pregnant mice
MicroRNA-122-5p Targets FOXO3 to Mediate Podocyte Senescence and Proteinuria Induced by Angiotensin II Type 1 Receptor Autoantibodies in Preeclampsia · Reproductive sciences (Thousand Oaks, Calif.) · 22 Sep 2026

Latest

1

Reproductive SciencesAnimals23 Sep

MicroRNA-122-5p Targets FOXO3 to Mediate Podocyte Senescence and Proteinuria Induced by Angiotensin II Type 1 Receptor Autoantibodies in Preeclampsia