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Anabolic therapies

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Lancet·11 Sep

Osteoporosis

ReviewOsteoporosis

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Antiresorptive therapies1
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Lilly’s retatrutide achieves 18.8% weight loss in obesity and type 2 diabetesTrialsMedical Xpress and 4 more

Blocking the protein PD-L2 reduces senescent cells and improves glucose regulation in miceResearchScienceDaily and 1 more

Human ovaries keep remodeling with increasing inflammation decades after menopause, researchers reportResearchMedical Xpress and 4 more

Trials

Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and WomenResults posted 13 Oct 2026, Marquette University Fisetin for Improving Vascular Function in Older Adults: A Phase II Clinical TrialPhase 2Registered 13 Oct 2026, University of Colorado, Boulder ELITE: Deep Profiling and Algorithmic Polytherapy to Map Individual Response in Healthy AgingPhase 2Registered 13 Oct 2026, Sheba Medical Center

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Depressive symptomsDisease26 papers this week, usually 4 LifestyleExposureGenetic risk and lifestyle linked to estimated brain aging PregnancyExposureEstimated brain-age gap rises by three years in pregnancy TERTGeneBlood-cell telomerase delays premature aging in zebrafish Vitamin DInterventionSevere vitamin D deficiency is linked to higher death rates Mediterranean lifestyleExposureMediterranean lifestyle linked to lower risk of death

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Mechanisms199 Interventions385 Biomarkers308 Populations517 AI & data93 Industry & policy21

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