(-)-α-bisabolol
- 1 lab in 1 country
- Funders: Guangdong Provincial Hospital of Traditional Chinese Medicine and 1 more
- Animals1
Outcomes
4Elastin and collagen III mRNA expression
upin mice1
1 study
Elastin and collagen III mRNA expression
upin mice1
(-)-α-bisabolol increases elastin and collagen III mRNA expression in mice.
“Furthermore, (-)-α-bis up-regulated the mRNA expression levels of elastin and collagen III effectively (P<0.05).”
Animalsaged BALB/c micegelskin0.5% and 2%30 days
Iranian journal of basic medical sciences1 Jan 2024
Skin barrier function
upin mice1
1 study
Skin barrier function
upin mice1
(-)-α-bisabolol improves skin barrier function in mice.
“Mice aged 9 months were applied locally with (-)-α-bis gel to improve skin aging, the TEWL and skin barrier index of dorsal skin”
Animalsaged BALB/c micegeldorsal skin0.5% and 2%30 days
Iranian journal of basic medical sciences1 Jan 2024
Senescence-associated secretory phenotype (SASP)
downin human cells1
1 study
Senescence-associated secretory phenotype (SASP)
downin human cells1
(-)-α-bisabolol decreases senescence-associated secretory phenotype (SASP) in human cells.
“(-)-α-Bis reduced the expression of senescence-associated β-galactosidase (SA-β-gal) and expression levels of SASP in HSF cells stimulated by D-Gal (P<0.05).”
CellsD-galactose-induced senescencehuman skin fibroblast
Iranian journal of basic medical sciences1 Jan 2024
Senescence-associated beta-galactosidase
downin human cells1
1 study
Senescence-associated beta-galactosidase
downin human cells1
(-)-α-bisabolol decreases senescence-associated beta-galactosidase in human cells.
“(-)-α-Bis reduced the expression of senescence-associated β-galactosidase (SA-β-gal) and expression levels of SASP in HSF cells stimulated by D-Gal (P<0.05).”
CellsD-galactose-induced senescencehuman skin fibroblast
Iranian journal of basic medical sciences1 Jan 2024