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Alizarin

Intervention

1 paper4 findings

MeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

Outcomes

4

Cellular senescence

downin rats1

1 study

  1. Alizarin decreases cellular senescence in rats.

    “significantly delayed the vascular senescence effect in hypertension”

    Animalsin hypertension

    The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence

    Life sciencesJun 23, 2024

More on Cellular senescence

Mitochondrial damage

downin rats1

1 study

  1. Alizarin decreases mitochondrial damage in rats.

    “inhibited oxidative stress-induced mitochondrial damage”

    Animalsin hypertension

    The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence

    Life sciencesJun 23, 2024

Endothelium-dependent relaxation

upin rats1

1 study

  1. Alizarin improves endothelium-dependent relaxation in rats.

    “increased endothelium-dependent relaxation (EDR) in SHR”

    Animalsin spontaneously hypertensive rats

    The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence

    Life sciencesJun 23, 2024

Systolic blood pressure

downin rats1

1 study

  1. Alizarin decreases systolic blood pressure in rats.

    “Alizarin not only restored SBP and increased endothelium-dependent relaxation (EDR) in SHR”

    Animalsin spontaneously hypertensive rats

    The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence

    Life sciencesJun 23, 2024

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