AGK-2
- 1 lab in 1 country
- Funder: Gazi Üniversitesi
- Animals1
Outcomes
4SIRT2
downin rats1
1 study
SIRT2
downin rats1
AGK-2 decreases SIRT2 in rats.
“AGK-2 treatment reduced SIRT2, TOS, OSI and caspase-3, and increased TAS particularly in aged rats.”
Animalsageingpancreas10 μM30 days
Archives of physiology and biochemistry17 Apr 2026
CASP3
downin rats1
1 study
CASP3
downin rats1
AGK-2 decreases CASP3 in rats.
“AGK-2 treatment reduced SIRT2, TOS, OSI and caspase-3, and increased TAS particularly in aged rats.”
Animalsageingpancreas10 μM30 days
Archives of physiology and biochemistry17 Apr 2026
Apoptosis
downin rats1
1 study
Apoptosis
downin rats1
AGK-2 decreases apoptosis in rats.
“AGK-2 reverses ageing-associated changes in pancreatic oxidative stress and apoptosis.”
Animalsageingpancreas10 μM30 days
Archives of physiology and biochemistry17 Apr 2026
Oxidative stress and ROS signalling
downin rats1
1 study
Oxidative stress and ROS signalling
downin rats1
AGK-2 decreases oxidative stress and ROS signalling in rats.
“AGK-2 treatment reduced SIRT2, TOS, OSI and caspase-3, and increased TAS particularly in aged rats.”
Animalsageingpancreas10 μM30 days
Archives of physiology and biochemistry17 Apr 2026
Latest
1 in 12 monthsArchives of Physiology and Biochemistry
Effects of AGK-2 treatment on sirtuin-2, oxidative stress and apoptosis in ageing pancreatic tissue of rats
Experiments in ratsSirtuin signalling
Aging Brain
The role of SIRT2 inhibition on the aging process of brain in male rats
Experiments in animalsMechanisms