Age at menarche

Exposure

3 papers3 findings

  • 2 independent labs in 1 country
  • Funder: National Natural Science Foundation of China
  • Humans3

Outcomes

1

anti-Müllerian hormone

upin humans1

1 study
  1. Age at menarche increases anti-Müllerian hormone in humans (0.04 ng/ml per year increase).

    “For every one-year increase in age at menarche, AMH increases by 0.04 ng/ml.”

    Humansfemales

    Age at menarche and age-adjusted anti-Müllerian hormone level among women of childbearing age in China

    Journal of ovarian research30 Mar 2026

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Associations

2

anti-Müllerian hormone

upin humans1OR 1.28

1 study
  1. Age at menarche is associated with anti-Müllerian hormone in humans (OR 1.28 (95% CI 1.07–1.54)).

    “women with age at menarche ≥ 14 years tend to have higher AMH level no matter in Middle AMH Group (OR, 1.28; 95%CI: 1.07–1.54)”

    Humansfemales

    Age at menarche and age-adjusted anti-Müllerian hormone level among women of childbearing age in China

    Journal of ovarian research30 Mar 2026

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Cardiometabolic disease

downin humans1OR 0.858

1 study
  1. Age at menarche lowers the risk of cardiometabolic disease in humans (OR 0.858, 95% CI 0.749-0.982).

    “Age at menarche of 16-18 years was a protective factor compared with ≤16 years of age (OR = 0.858, 95% CI: 0.749-0.982).”

    Humanscompared with ≤16 years of agefemalesn = 6,407

    Reproductive factors and cardiometabolic disease among middle-aged and older women: a nationwide study from CHARLS

    Frontiers in cardiovascular medicine30 Apr 2024

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