AAV9 mutant MACROH2A1

Intervention1 paper2 findings

Animals1

Outcomes

2

Marrow fat accumulation

downin mice1Very low certainty

1 study

AAV9 mutant MACROH2A1 decreases marrow fat accumulation in mice.
Animalsin OVX osteoporotic micebone marrow
Lactylation of histone variant MacroH2A1 at K134 regulates osteogenic differentiation of bone marrow mesenchymal stem cells · Research Square · 17 Sep 2026 · Preprint

Trabecular bone mass

upin mice1Very low certainty

1 study

AAV9 mutant MACROH2A1 increases trabecular bone mass in mice.
Animalsin OVX osteoporotic micebone marrow
Lactylation of histone variant MacroH2A1 at K134 regulates osteogenic differentiation of bone marrow mesenchymal stem cells · Research Square · 17 Sep 2026 · Preprint

Latest

1

Research SquareAnimalsPreprint18 Sep

Lactylation of histone variant MacroH2A1 at K134 regulates osteogenic differentiation of bone marrow mesenchymal stem cells

Stem cell differentiation