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AAV-PTPN1-RNAI

Intervention

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

1

Age-related bone loss

downin mice1

1 study

  1. AAV-PTPN1-RNAI decreases age-related bone loss in mice.

    “Targeted inhibition of PTP1B with AAV-Ptpn1-RNAi dramatically postponed age-related bone loss in middle-aged mice.”

    Animalsbone

    The age-related characteristics in bone microarchitecture, osteoclast distribution pattern, functional and transcriptomic alterations of BMSCs in mice

    Mechanisms of ageing and developmentOct 12, 2023

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