77pd quinone

  • 1 lab in 1 country
  • Funder: National Key Research and Development Program of China
  • Model organisms1

Outcomes

3

Mitochondrial unfolded protein response

downin worms1

1 study
  1. 77pd quinone inhibits mitochondrial unfolded protein response in worms.

    “expressions of hsp-6/60, mitochondrial UPR (mt UPR) marker genes, were inhibited by 10 μg/L 77PDQ, suggesting induction of suppression in mt UPR”

    Model organisms10 μg/L

    Exposure to 77PD quinone inhibits longevity and healthspan via affecting mitochondrial signals in Caenorhabditis elegans

    Ecotoxicology and environmental safety19 Jan 2026

More on Mitochondrial unfolded protein response

Healthspan

downin worms1

1 study
  1. 77pd quinone impairs healthspan in worms.

    “inhibited healthspan indicated by change of locomotion behavior during the aging”

    Model organisms0.1-10 μg/L

    Exposure to 77PD quinone inhibits longevity and healthspan via affecting mitochondrial signals in Caenorhabditis elegans

    Ecotoxicology and environmental safety19 Jan 2026

Lifespan

downin worms1

1 study
  1. 77pd quinone shortens lifespan in worms.

    “Exposure to 0.1-10 μg/L 77PDQ reduced lifespan”

    Model organisms0.1-10 μg/L

    Exposure to 77PD quinone inhibits longevity and healthspan via affecting mitochondrial signals in Caenorhabditis elegans

    Ecotoxicology and environmental safety19 Jan 2026

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