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2-butoxytetrahydrofuran

2-butoxytetrahydrofuran has been studied in 1 paper since 2022: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Nov 9, 2022: “2-Butoxytetrahydrofuran and Palmitic Acid from Holothuria scabra Enhance C. elegans Lifespan and Healthspan via DAF-16/FOXO and SKN-1/NRF2 Signaling Pathways”.

Intervention

1 paper studies it2 findingsUpdated

PubChem

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Mahidol University and 1 more
  • Model organisms1

What did studies of 2-butoxytetrahydrofuran find?

2

Studies of 2-butoxytetrahydrofuran measured 2 outcomes; the most studied are oxidative stress and ROS signaling (1 study) and lifespan (1).

Oxidative stress and ROS signaling

downin worms1

1 study

  1. 2-butoxytetrahydrofuran protects against oxidative stress and ROS signaling in worms.

    “2-BTHF and palmitic acid were able to enhance resistance to paraquat-induced oxidative stress and thermal stress”

    Model organismsparaquat-induced oxidative stress

    2-Butoxytetrahydrofuran and Palmitic Acid from Holothuria scabra Enhance C. elegans Lifespan and Healthspan via DAF-16/FOXO and SKN-1/NRF2 Signaling Pathways

    Pharmaceuticals (Basel, Switzerland)

More on Oxidative stress and ROS signaling

Lifespan

upin worms1

1 study

  1. 2-butoxytetrahydrofuran extends lifespan in worms.

    “2-BTHF and palmitic acid could significantly extend lifespan of wild type C. elegans”

    Model organismswild type

    2-Butoxytetrahydrofuran and Palmitic Acid from Holothuria scabra Enhance C. elegans Lifespan and Healthspan via DAF-16/FOXO and SKN-1/NRF2 Signaling Pathways

    Pharmaceuticals (Basel, Switzerland)

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