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ZRANB3

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Cancer Institute and 1 more
  • Animals1

Effects

1

Hematopoietic dysregulation

downin mice1

1 study

  1. ZRANB3 protects against hematopoietic dysregulation in mice.

    “Aging significantly worsened these hematopoiesis defects in Zranb3-deficient mice, including accelerating the onset of myeloid-biased hematopoietic dysregulation to early in life.”

    Animalsshown by deficiency/lossbone marrow

    DNA fork remodeling proteins, Zranb3 and Smarcal1, are uniquely essential for aging hematopoiesis

    Aging cellJul 23, 2024

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