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ZONULIN-1

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Consorzio Interuniversitario Biotecnologie and 7 more
  • Animals1

Interventions

1

Methylglyoxal

downin mice1

1 study

  1. Methylglyoxal decreases ZONULIN-1 in mice.

    “reduced expression and delocalization of zonulin-1 and occludin, tight junction proteins”

    Animalsoral100 mg/kg/day4 weeks

    Effects of methylglyoxal on intestine and microbiome composition in aged mice

    Food and chemical toxicology : an international journal published for the British Industrial Biological Research AssociationJan 23, 2025

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