USP34

1 paper2 findings

1 lab in 1 country

Funders: National Key Research and Development Program of China and 1 more

Animals1

Effects

1

Wnt/β-catenin signalling

downin mice1

1 study

USP34 decreases wnt/β-catenin signalling in mice.
“Inhibition of Usp34 downregulated the Wnt/β-catenin pathway, promoting lipid droplet formation and differentiation of PDGFRα+ progenitor cells.”
Animalsin PDGFRα+ progenitor cells
From Gut to Fat: Intestinal Epithelial Exosomes Target PDGFRα⁺ Progenitors to Promote Lipogenesis and Counteract Subcutaneous Adipose Tissue Atrophy in Aging
Aging cell1 Jul 2026

More on Wnt/β-catenin signalling

Upstream

1

MIR379

downin mice1

1 study

MIR379 inhibits USP34 in mice.
“young SI-Exos were enriched with miR-379-5p, which targeted Usp34, a negative regulator of lipogenesis.”
Animalsin PDGFRα+ progenitor cells
From Gut to Fat: Intestinal Epithelial Exosomes Target PDGFRα⁺ Progenitors to Promote Lipogenesis and Counteract Subcutaneous Adipose Tissue Atrophy in Aging
Aging cell1 Jul 2026

Latest

1 in 12 months

Aging Cell13 Jul

From Gut to Fat: Intestinal Epithelial Exosomes Target PDGFRα⁺ Progenitors to Promote Lipogenesis and Counteract Subcutaneous Adipose Tissue Atrophy in Aging

Experiments in miceGut and microbiome