AgingResearch.NewsJoin free

TS65DNGENOTYPE

Gene

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: National Institute on Aging
  • Animals1

Effects

1

Soluble Aβ40−42

upin mice1

1 study

  1. TS65DNGENOTYPE increases soluble Aβ40−42 in mice.

    “trisomic mice accumulate soluble Aβ40−42 in the basal forebrain, frontal cortex, hippocampus, and cerebellum in an age-specific manner, with elevation in the frontal cortex and hippocampus as early as 4 months of age”

    Animalstrisomybrain

    Temporal and brain region-specific elevations of soluble Amyloid-β₄₀₋₄₂ in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease

    Aging cell

More on Soluble Aβ40−42

Latest

Related