THEMIS

2 papers2 findings

HGNC NCBI Gene Taxon

1 lab in 1 country

Funder: University of Michigan

Humans1
Animals1

Effects

2

Cellular senescence

downin mice1

1 study

THEMIS inhibits cellular senescence in mice.
“Genetic ablation of Themis, either globally or specifically in hepatocytes, resulted in significant expansion of daHep and senescent hepatocyte populations”
Animalsshown by knockoutliver
THEMIS attenuates MASH by suppressing disease-associated hepatocyte induction and hepatocyte senescence in mice
The Journal of clinical investigation1 May 2026

More on Cellular senescence

Metabolic dysfunction-associated steatohepatitis

downin mice1

1 study

THEMIS protects against metabolic dysfunction-associated steatohepatitis in mice.
“Genetic ablation of Themis, either globally or specifically in hepatocytes, resulted in significant expansion of daHep and senescent hepatocyte populations and exacerbated MASH pathology in mice.”
Animalsshown by knockoutliver
THEMIS attenuates MASH by suppressing disease-associated hepatocyte induction and hepatocyte senescence in mice
The Journal of clinical investigation1 May 2026

More on Metabolic dysfunction-associated steatohepatitis

Latest

2 in 12 months

The Journal of Clinical Investigation1 May

THEMIS attenuates MASH by suppressing disease-associated hepatocyte induction and hepatocyte senescence in mice

Experiments in miceCellular senescence

AAIC 2025 Abstract26 Dec

Identification of candidate serum protein biomarkers in Down's syndrome dementia

Case-control study of 50 peopleDown syndrome