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THAP11

There is 1 paper on THAP11 in aging research: none in people yet, 1 in animals.

Gene

1 paper studies it1 finding

HGNCNCBI GeneTaxon

See all 1 papers on THAP11

At a glance

The findings reach worms or flies, none yet in people. 1 lab in 1 country.

Worms or flies: a single group. Cells, mice and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 4 more
  • Model organisms1

Effects

1

Survival

downin flies1

1 study

  1. THAP11 decreases survival in flies (transgenic expression of THAP11-polyQ).

    “expression of THAP11-polyQ in transgenic flies leads to progressive neuronal cell loss, locomotor deficiency, and reduced survival”

    Model organismstransgenic expression of THAP11-polyQ

    Rapamycin alleviates neurodegeneration in a Drosophila model of spinocerebellar ataxia type 51

    Journal of genetics and genomics = Yi chuan xue bao

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