TESPA1

2 papers study it1 finding

1 lab in 1 country

Funders: Foundation for the National Institutes of Health and 5 more

Humans2

Effects

1

Hippocampus volume

downin humans1

1 study

TESPA1 decreases hippocampus volume in humans (p < 0.01).
“The allele C of rs4374022 was associated with DNAmTL shortening, lower hippocampus volume (p < 0.01), and decreased mRNA expression in hippocampus tissue (p = 0.04).”
Humans
Alcohol use disorder is associated with DNA methylation-based shortening of telomere length and regulated by TESPA1: implications for aging
Molecular psychiatryJun 15, 2022

Latest

Journal of Crohn's & ColitisAug 28

Analysis of Systemic Epigenetic Alterations in Inflammatory Bowel Disease: Defining Geographical, Genetic and Immune-Inflammatory influences on the Circulating Methylome

Case-control study of 295 peopleInflammatory bowel disease

Molecular PsychiatryJun 16

Alcohol use disorder is associated with DNA methylation-based shortening of telomere length and regulated by TESPA1: implications for aging

Cohort study of 4,219 peopleTelomere length