SLC24A4

Gene

1 paper2 findings

  • 1 lab
  • Animals1

Effects

2

Vascular calcification

downin mice1

1 study
  1. SLC24A4 protects against vascular calcification in mice.

    “Aged-related loss of NCKX4 impaired Ca2+ clearance function and increased Ca2+-phosphate mineralization.”

    Animalsshown by knockout or age-related loss

    Age-related decline in NCKX4-mediated calcium clearance accelerates aortic remodelling and drives early vascular ageing

    The Journal of physiology20 Feb 2026

More on Vascular calcification

Arterial remodelling

downin mice1

1 study
  1. SLC24A4 protects against arterial remodelling in mice.

    “young (12-15 weeks) Nckx4-/- mice exhibited elastic fibre fragmentation, collagen accumulation, arterial wall thickening and extracellular matrix (ECM) remodelling”

    Animalsshown by knockoutarterial wall

    Age-related decline in NCKX4-mediated calcium clearance accelerates aortic remodelling and drives early vascular ageing

    The Journal of physiology20 Feb 2026

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