SLC24A4
1 paper2 findings
- 1 lab
- Animals1
Effects
2Vascular calcification
downin mice1
1 study
Vascular calcification
downin mice1
SLC24A4 protects against vascular calcification in mice.
“Aged-related loss of NCKX4 impaired Ca2+ clearance function and increased Ca2+-phosphate mineralization.”
Animalsshown by knockout or age-related loss
The Journal of physiology20 Feb 2026
Arterial remodelling
downin mice1
1 study
Arterial remodelling
downin mice1
SLC24A4 protects against arterial remodelling in mice.
“young (12-15 weeks) Nckx4-/- mice exhibited elastic fibre fragmentation, collagen accumulation, arterial wall thickening and extracellular matrix (ECM) remodelling”
Animalsshown by knockoutarterial wall
The Journal of physiology20 Feb 2026
Latest
1 in 12 monthsThe Journal of Physiology
Age-related decline in NCKX4-mediated calcium clearance accelerates aortic remodelling and drives early vascular ageing
Experiments in miceExtracellular matrix remodelling