There are 8 papers on SLC12A3 in aging research: 2 observational studies in people, 4 in animals, 1 review.
At a glance
The findings reach mice, none yet in people. 1 lab in 1 country; 18 trials, 14 with no results posted.
Mice: a single group. Cells, worms or flies and humans: nothing yet.
- 1 lab in 1 country
- 18 trials, 14 with no results posted
- Funders: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior and 2 more
- 16 of 18 trials sponsored by developers of drugs aimed at it
- Humans2
- Animals4
Interventions
1Water deprivation
downin rats1
1 study
Water deprivation
downin rats1
Water deprivation decreases SLC12A3 in rats.
“the WD 18-month-old males displayed a lower relative expression of Slc12a3 mRNA and higher α-SMA expression than the control 18-month-old males.”
Animalskidney48 hmales
Alterations in Kidney Structures Caused by Age Vary According to Sex and Dehydration Condition
International journal of molecular sciences
Latest
1 paper in 12 monthsCirculation Research
Experimental TET2 Clonal Hematopoiesis Predisposes to Renal Hypertension Through an Inflammasome-Mediated Mechanism
Experiments in miceNLRP3 inflammasome
International Journal of Molecular Sciences
Alterations in Kidney Structures Caused by Age Vary According to Sex and Dehydration Condition
Experiments in ratsKidney
PLOS Genetics
Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci
Genetic association study of 81,246 peopleFish oil
Oxidative Medicine and Cellular Longevity
Impact on Longevity of Genetic Cardiovascular Risk and Lifestyle including Red Meat Consumption
Case-control study of 521 peopleCardiovascular disease