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Sestrin

There is 1 paper on Sestrin in aging research: none in people yet, 1 in animals.

Gene

1 paper studies it1 finding

Taxon

See all 1

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Heart, Lung, and Blood Institute and 4 more
  • Model organisms1

Effects

1

Autophagy

upin flies1

1 study

  1. Sestrin increases autophagy in SCA2 flies, even without exercise.

    “coincident with disease protein level reduction and increased autophagic flux”

    Model organismsin SCA2 flies, even without exercise

    Endurance exercise ameliorates phenotypes in Drosophila models of spinocerebellar ataxias

    eLife

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