SAC1

SAC1 is required for replicative lifespan in yeast cells.

“deficiency of SAC1 or ATG8, two essential components of the autophagy process, decreased the cell proliferation ability of the long-lived pmt1Δ yeast cells, and prevented the lifespan extension.”

Cellsin pmt1Δ yeast cells

Effect of ATG8 or SAC1 deficiency on the cell proliferation and lifespan of the long-lived PMT1 deficiency yeast cells

FEMS microbiology letters·9 Jan 2024