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rst2

Gene

1 paper2 findings

Taxon 4896

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

A gene’s or a process’s line counts the gene with the processes named after it, as NLRP3 with the NLRP3 inflammasome, and the trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: China Scholarship Council and 1 more
  • Cells1

Effects

1

carbon metabolism genes

is required forin fission yeast cells1

1 study

  1. rst2 is required for carbon metabolism genes in fission yeast cells.

    “Rst2 was required for the induction of carbon metabolism genes and maintained nuclear localization in CAP-treated stationary-phase cells.”

    Cellsin chloramphenicol-treated stationary-phase cells

    Mitochondrial Translation Inhibition Triggers an Rst2-Controlled Transcriptional Reprogramming of Carbon Metabolism in Stationary-Phase Cells of Fission Yeast

    Biomolecules24 Sep 2025

Associations

1

Lifespan

mixedin fission yeast cells1

1 study

  1. rst2 is associated with lifespan in fission yeast cells.

    “The transcription factors Scr1 and Rst2, regulators of carbon catabolite repression (CCR), controlled a common set of carbon metabolism genes in CAP-treated stationary-phase cells, and they showed opposing effects on the lifespan of these cells.”

    Cellsin chloramphenicol-treated stationary-phase cells

    Mitochondrial Translation Inhibition Triggers an Rst2-Controlled Transcriptional Reprogramming of Carbon Metabolism in Stationary-Phase Cells of Fission Yeast

    Biomolecules24 Sep 2025

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