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Rok

Gene

1 paper1 finding

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Boston College and 4 more
  • Model organisms1

Effects

1

Multinucleation

downin flies1

1 study

  1. Rok prevents multinucleation in flies.

    “knockdown of Rho kinase, E-cadherin or α-catenin is sufficient to induce multinucleation in young animals”

    Model organismsin young animalsabdominal epithelium

    Epithelial mechanics are maintained by inhibiting cell fusion with age in Drosophila

    Journal of cell science16 Oct 2023

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