PRPF19

3 papers2 findings

HGNC NCBI Gene Taxon

1 lab in 1 country

Funder: Austrian Science Fund

Animals2

Effects

1

Colony formation

upin mouse cells1

1 study

PRPF19 increases colony formation in mouse cells.
“primary and secondary colonies were significantly less formed from SNEV(+/-) cells, a defect that was rescued by ectopic SNEV expression.”
CellsLin(-) cells derived from heterozygous SNEV knockout mice
Haploinsufficiency of senescence evasion factor causes defects of hematopoietic stem cells functions
Stem cells and development1 Apr 2008

Associations

1

Lineage-depleted precursor cells

upin mice1

1 study

PRPF19 is associated with lineage-depleted precursor cells in mice.
“murine SNEV mRNA expression is high in lineage-depleted (Lin(-)) precursor cells of the bone marrow immediately after isolation as compared to fully differentiated peripheral blood lymphocytes (PBLs).”
AnimalsLin(-) precursor cells compared to PBLs
Haploinsufficiency of senescence evasion factor causes defects of hematopoietic stem cells functions
Stem cells and development1 Apr 2008

Latest

1 in 12 months

Renal Failure1 Jun

Combining bioinformatics and machine learning to analyze and validate sepsis-related cell senescence genes and potential drugs

Experiments in animalsSepsis

Stem Cells and Development1 Apr

Haploinsufficiency of senescence evasion factor causes defects of hematopoietic stem cells functions

Experiments in miceStem cell maintenance

Nucleic Acids Research14 Dec

Contributions of DNA interstrand cross-links to aging of cells and organisms

ReviewMechanisms