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prp-19

Gene

1 paper studies it3 findings

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Howard Hughes Medical Institute and 2 more
  • Model organisms1

Effects

1

Mitochondrial unfolded protein response

is required forin worms1

1 study

  1. prp-19 is required for mitochondrial unfolded protein response in worms.

    “splicing factors such as Precursor RNA processing 19 (PRP-19) are required for the induction of UPRmt in C. elegans”

    Model organisms

    Splicing factor PRP-19 regulates mitochondrial stress response

    Life metabolism

More on Mitochondrial unfolded protein response

Associations

2

Immune response

mixedin worms1

1 study

  1. prp-19 is associated with immune response in worms.

    “PRP-19 also modulates mitochondrial perturbation-induced innate immune response and lifespan extension”

    Model organismsin response to mitochondrial perturbation

    Splicing factor PRP-19 regulates mitochondrial stress response

    Life metabolism

More on Immune response

Lifespan

mixedin worms1

1 study

  1. prp-19 is associated with lifespan in worms.

    “PRP-19 also modulates mitochondrial perturbation-induced innate immune response and lifespan extension”

    Model organismsin response to mitochondrial perturbation

    Splicing factor PRP-19 regulates mitochondrial stress response

    Life metabolism

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