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PRCP

Gene

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: University of Mississippi
  • Cells1

Upstream

1

Cellular senescence

downin human cells1

1 study

  1. Cellular senescence decreases PRCP in human cells.

    “The NO production and expression of both PRCP and eNOS increased in early-passage HPAECs and decreased in late-passage HPAECs.”

    Cellslate-passage senescent HPAECsendothelial cells

    Increased Prolylcarboxypeptidase Expression Can Serve as a Biomarker of Senescence in Culture

    Molecules (Basel, Switzerland)May 9, 2024

More on Cellular senescence

Associations

2

Respiration rate

mixedin human cells1

1 study

  1. PRCP is associated with respiration rate in human cells.

    “with an increase in the passage number of HPAECs, reduced PRCP altered the respiration rate”

    Cellsin late-passage HPAECsendothelial cells

    Increased Prolylcarboxypeptidase Expression Can Serve as a Biomarker of Senescence in Culture

    Molecules (Basel, Switzerland)May 9, 2024

More on Respiration rate

TERT

downin human cells1

1 study

  1. PRCP is associated with TERT in human cells.

    “Low activity of PRCP in late-passage HPAECs was associated with rapid decreased telomerase reverse transcriptase mRNA levels.”

    Cellslate-passage HPAECsendothelial cells

    Increased Prolylcarboxypeptidase Expression Can Serve as a Biomarker of Senescence in Culture

    Molecules (Basel, Switzerland)May 9, 2024

More on TERT

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