PERP
- 1 lab in 1 country
- Funders: National Natural Science Foundation of China and 1 more
- Animals1
Effects
2Apoptosis
upin mice1
1 study
Apoptosis
upin mice1
PERP induces apoptosis in mice.
“The PERP protein functions in apoptosis induction and as a tumor suppressor”
Reviewconditional knockout of Perp
Perp Deficiency Induces Defective Negative Selection and Autoimmune Arthritis in Aged Mice
Aging cell23 Apr 2026
Autoimmune arthritis
downin mice1
1 study
Autoimmune arthritis
downin mice1
PERP protects against autoimmune arthritis in mice.
“middle-aged floxed mice exhibited excessive accumulation of activated CD4+ T-cells in peripheral blood, alongside T cell-mediated autoimmune arthritis.”
Animalsconditional knockout of Perp
Perp Deficiency Induces Defective Negative Selection and Autoimmune Arthritis in Aged Mice
Aging cell23 Apr 2026
Latest
1 in 12 monthsAging Cell
Perp Deficiency Induces Defective Negative Selection and Autoimmune Arthritis in Aged Mice
Experiments in miceMechanisms