PERP

Gene

1 paper2 findings

HGNCNCBI GeneTaxon

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Animals1

Effects

2

Apoptosis

upin mice1

1 study
  1. PERP induces apoptosis in mice.

    “The PERP protein functions in apoptosis induction and as a tumor suppressor”

    Reviewconditional knockout of Perp

    Perp Deficiency Induces Defective Negative Selection and Autoimmune Arthritis in Aged Mice

    Aging cell23 Apr 2026

More on Apoptosis

Autoimmune arthritis

downin mice1

1 study
  1. PERP protects against autoimmune arthritis in mice.

    “middle-aged floxed mice exhibited excessive accumulation of activated CD4+ T-cells in peripheral blood, alongside T cell-mediated autoimmune arthritis.”

    Animalsconditional knockout of Perp

    Perp Deficiency Induces Defective Negative Selection and Autoimmune Arthritis in Aged Mice

    Aging cell23 Apr 2026

More on Autoimmune arthritis

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