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PERK

Gene

1 paper1 finding

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: University Grants Commission and 2 more
  • Model organisms1

Upstream

1

SNCA

downin flies1

1 study

  1. SNCA decreases PERK in flies.

    “observed a decrease in the expression of PERK (Protein kinase R-like ER kinase) during ER stress”

    Model organismsduring ER stress in Drosophila PD model

    H50Q mutation in alpha-Synuclein impairs the insulin signaling pathway and induces neuroinflammation in the Drosophila model

    Experimental cell researchFeb 20, 2025

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