pdr-1

1. pdr-1 increases mitochondrial Ca2+ in worms.

   Model organismsin muscle cellsbody-wall muscle

   Mitochondrial Ca²⁺ Influx via MCU-1 Contributes to Oxidative Mitochondrial Defects in PDR-1/Parkin-Deficient Caenorhabditis elegans Body-Wall Muscle · Antioxidants (Basel, Switzerland) · 21 Aug 2026

Mitochondrial Ca2+ →

1. pdr-1 decreases mitochondrial membrane potential in worms.

   Model organismsin muscle cellsbody-wall muscle

   Mitochondrial Ca²⁺ Influx via MCU-1 Contributes to Oxidative Mitochondrial Defects in PDR-1/Parkin-Deficient Caenorhabditis elegans Body-Wall Muscle · Antioxidants (Basel, Switzerland) · 21 Aug 2026

Mitochondrial membrane potential →

1. pdr-1 increases mitochondrial reactive oxygen species in worms.

   Model organismsin muscle cellsbody-wall muscle

   Mitochondrial Ca²⁺ Influx via MCU-1 Contributes to Oxidative Mitochondrial Defects in PDR-1/Parkin-Deficient Caenorhabditis elegans Body-Wall Muscle · Antioxidants (Basel, Switzerland) · 21 Aug 2026

Mitochondrial reactive oxygen species →

1. pdr-1 impairs locomotor activity in worms.

   Model organismslater in adulthood

   Mitochondrial Ca²⁺ Influx via MCU-1 Contributes to Oxidative Mitochondrial Defects in PDR-1/Parkin-Deficient Caenorhabditis elegans Body-Wall Muscle · Antioxidants (Basel, Switzerland) · 21 Aug 2026