PDLIM5

1 paper2 findings

1 lab in 1 country

Funders: Health Commission of Zhejiang Province and 1 more

Animals1

Interventions

1

Melatonin

downin mice1

1 study

Melatonin decreases PDLIM5 in mice.
“Pdlim5 downregulation”
Animalsin aged mice10 mg/kg1 week
Aging-Induced Episodic-Like Memory Impairment Could be Alleviated by Melatonin Treatment via Preserving Blood-Brain Barrier Integrity and Upregulating CRTC1
CNS neuroscience & therapeutics1 Apr 2025

More on Melatonin

Effects

1

Episodic-like memory

downin mice1

1 study

PDLIM5 impairs episodic-like memory in mice.
“aging-related memory impairment in the NOR task was significantly reduced in Pdlim5-/- mice”
Animalsshown by knockout
Aging-Induced Episodic-Like Memory Impairment Could be Alleviated by Melatonin Treatment via Preserving Blood-Brain Barrier Integrity and Upregulating CRTC1
CNS neuroscience & therapeutics1 Apr 2025

Latest

CNS Neuroscience & Therapeutics26 Apr

Aging-Induced Episodic-Like Memory Impairment Could be Alleviated by Melatonin Treatment via Preserving Blood-Brain Barrier Integrity and Upregulating CRTC1

Experiments in miceMelatonin