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pch-2

Gene

1 paper3 findings

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Against: findings that point the other way from most findings on the same outcome.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • 1 finding against
  • Funder: Yale University
  • Model organisms1

Effects

2

Lifespan

downin worms1upin worms1

1 study

  1. pch-2 shortens lifespan in worms.

    “reducing pch-2 expression with RNAi shortens worm lifespan”

    Model organismsRNAi knockdown

    PCH-2 regulates Caenorhabditis elegans lifespan

    Aging1 Jan 2015

  2. pch-2 extends lifespan in worms.

    “pch-2 overexpression in C. elegans extends worm lifespan”

    Model organismsoverexpression

    PCH-2 regulates Caenorhabditis elegans lifespan

    Aging1 Jan 2015

Survival

upin worms1

1 study

  1. pch-2 improves survival in worms.

    “pch-2 overexpression in C. elegans extends worm lifespan, and enhances worm survival in response to various stressors”

    Model organismsoverexpression

    PCH-2 regulates Caenorhabditis elegans lifespan

    Aging1 Jan 2015

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