mxl-2
- 1 lab in 1 country
- Funders: Centre International de Recherche sur le Cancer and 3 more
- Model organisms1
Effects
3Oxygen consumption rate
no changein worms1
1 study
Oxygen consumption rate
no changein worms1
mxl-2 has no effect on oxygen consumption rate in worms.
“loss of mxl-2 in DR does not affect the rate of oxygen consumption in young animals.”
Model organismsshown by mxl-2 loss under dietary restriction
GeroScience15 Jun 2024
Brood size
upin worms1
1 study
Brood size
upin worms1
mxl-2 increases brood size in worms.
“eat-2;mxl-2 animals exhibit substantially smaller brood sizes and lay a proportion of dead eggs”
Model organismsshown by mxl-2 loss in eat-2 dietary restriction animals
GeroScience15 Jun 2024
Dietary restriction-induced metabolic gene expression changes
is required forin worms1
1 study
Dietary restriction-induced metabolic gene expression changes
is required forin worms1
mxl-2 is required for dietary restriction-induced metabolic gene expression changes in worms.
“demonstrate broad changes in metabolic gene expression in eat-2 DR animals, which requires both mxl-2 and pha-4.”
Model organismseat-2 genetic model of dietary restriction
GeroScience15 Jun 2024